Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002019.4

p.R159Q

c.476G>A

Surrounding Variants

1 paper

NM_002019.4

p.R159W

c.475C>T

1 paper

NM_002019.4

p.C158C

c.474C>T

1 paper

NM_002019.4

p.T161T

c.483G>A

1 paper

NM_002019.4

p.V155I

c.463G>A

1 paper

NM_002019.4

p.L154R

c.461T>G

8 papers

NM_002019.4

p.L154F

c.460C>T

1 paper

NM_002019.4

p.L154I

c.460C>A

1 paper

NM_002019.4

p.G151R

c.451G>C

1 paper

NM_002019.4

p.G151R

c.451G>A

1 paper

NM_002019.4

p.T149T

c.447T>A

1 paper

NM_002019.4

p.M148I

c.444G>T

1 paper

NM_002019.4

p.M148I

c.444G>C