Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002019.4

p.M138R

c.413T>G

Surrounding Variants

1 paper

NM_002019.4

p.M138I

c.414G>T

1 paper

NM_002019.4

p.M138I

c.414G>C

1 paper

NM_002019.4

p.M138I

c.414G>A

1 paper

NM_002019.4

p.E137D

c.411G>C

1 paper

NM_002019.4

p.Y139C

c.416A>G

1 paper

NM_002019.4

p.Y139*

c.417C>G

1 paper

NM_002019.4

p.Y139*

c.417C>A

1 paper

NM_002019.4

p.S140C

c.418A>T

1 paper

NM_002019.4

p.V136I

c.406G>A

3 papers

NM_002019.4

p.F135L

c.405C>G

1 paper

NM_002019.4

p.F135L

c.405C>A

1 paper

NM_002019.4

p.F135Y

c.404T>A