Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.Y105_S106delFs

c.313_317del5

Surrounding Variants

1 paper

NM_002019.4

p.T102_K108insFs

c.304_323dup20

1 paper

NM_002019.4

p.G103D

c.308G>A

1 paper

NM_002019.4

p.V112E

c.335T>A

1 paper

NM_002019.4

p.T114I

c.341C>T

3 papers

NM_002019.4

p.T114N

c.341C>A

1 paper

NM_002019.4

p.K117*

c.349A>T

1 paper

NM_002019.4

p.K118M

c.353A>T

1 paper

NM_002019.4

p.T93I

c.278C>T

1 paper

NM_002019.4

p.T93S

c.278C>G

1 paper

NM_002019.4

p.T120K

c.359C>A

1 paper

NM_002019.4

p.T93S

c.277A>T

1 paper

NM_002019.4

p.E121*

c.361G>T