Varaico: Literature-Extracted Genetic Variants

FLT1

774 papers

RefSeq Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding re...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–138UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 238–324UCSCImmunoglobulin domain

I-setaa 337–426UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 425–554UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 560–640UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 1

HGNC Alias Symbol

VEGFR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002019.4

p.E56insFs

c.166dupG

Surrounding Variants

1 paper

NM_002019.4

p.E56fs

c.166_167fs

7 papers

NM_002019.4

p.R54S

c.162G>T

8 papers

NM_002019.4

p.R54S

c.162G>C

1 paper

NM_002019.4

p.K60N

c.180A>T

1 paper

NM_002019.4

p.K60N

c.180A>C

1 paper

NM_002019.4

p.P64S

c.190C>T

1 paper

NM_002019.4

p.M66I

c.198G>T

1 paper

NM_002019.4

p.M66I

c.198G>C

1 paper

NM_002019.4

p.M66I

c.198G>A

1 paper

NM_002019.4

p.V67L

c.199G>T

1 paper

NM_002019.4

p.V67L

c.199G>C

1 paper

NM_002019.4

p.V67_S68delFs

c.201_204del4