Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_004119.3

p.G846S

c.2536G>A

Surrounding Variants

1 paper

NM_004119.3

p.G846C

c.2536G>T

2 papers

NM_004119.3

p.G846R

c.2536G>C

1 paper

NM_004119.3

p.G846V

c.2537G>T

1 paper

NM_004119.3

p.R845S

c.2535G>T

1 paper

NM_004119.3

p.G846A

c.2537G>C

1 paper

NM_004119.3

p.R845S

c.2535G>C

7 papers

NM_004119.3

p.G846D

c.2537G>A

15 papers

NM_004119.3

p.R845G

c.2533A>G

1 paper

NM_004119.3

p.N847H

c.2539A>C

1 paper

NM_004119.3

p.N847T

c.2540A>C

1 paper

NM_004119.3

p.V844_R845ins4

c.2530_2534ins12

2 papers

NM_004119.3

p.N847_A848Splc

c.2541+1G>A