Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_004119.3

p.M837_S838del1

c.2510_2512delTCA

Surrounding Variants

1 paper

NM_004119.3

p.S838N

c.2513G>A

10 papers

NM_004119.3

p.I836_M837del2

c.2506_2510del6

2 papers

NM_004119.3

p.S838R

c.2514T>G

2 papers

NM_004119.3

p.S838R

c.2514T>A

1 paper

NM_004119.3

p.S838delFs

c.2513delC

2 papers

NM_004119.3

p.S838G

c.2512A>G

2 papers

NM_004119.3

p.S838R

c.2512A>C

3 papers

NM_004119.3

p.D839Y

c.2515G>T

2 papers

NM_004119.3

p.M837I

c.2511G>T

7 papers

NM_004119.3

p.D839H

c.2515G>C

2 papers

NM_004119.3

p.M837I

c.2511G>C

8 papers

NM_004119.3

p.D839N

c.2515G>A