Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.I836insFs

c.2507dupT

Surrounding Variants

1 paper

NM_004119.3

p.I836I

c.2508C>T

31 papers

NM_004119.3

p.I836M

c.2508C>G

1 paper

NM_004119.3

p.I836fs

c.2506_2507fs

1 paper

NM_004119.3

p.I836I

c.2508C>A

2 papers

NM_004119.3

p.I836ins1

c.2507_2508insGCC

4 papers

NM_004119.3

p.I836S

c.2507T>G

7 papers

NM_004119.3

p.I836T

c.2507T>C

3 papers

NM_004119.3

p.I836N

c.2507T>A

1 paper

NM_004119.3

p.M837L

c.2509A>T

1 paper

NM_004119.3

p.M837L

c.2509A>C

1 paper

NM_004119.3

p.D835_M837delins

c.2505_2509delinsCC

2 papers

NM_004119.3

p.M837T

c.2510T>C