Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.V825M

c.2473G>A

Surrounding Variants

1 paper

NM_004119.3

p.V825A

c.2474T>C

1 paper

NM_004119.3

p.V824M

c.2470G>A

1 paper

NM_004119.3

p.K823K

c.2469A>G

1 paper

NM_004119.3

p.K826N

c.2478G>T

1 paper

NM_004119.3

p.K826N

c.2478G>C

1 paper

NM_004119.3

p.K823I

c.2468A>T

1 paper

NM_004119.3

p.K823E

c.2467A>G

1 paper

NM_004119.3

p.G822E

c.2465G>A

2 papers

NM_004119.3

p.C828R

c.2482T>C

4 papers

NM_004119.3

p.C828S

c.2482T>A

1 paper

NM_004119.3

p.G822W

c.2464G>T

3 papers

NM_004119.3

p.G822R

c.2464G>C