Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.H821N

c.2461C>A

Surrounding Variants

1 paper

NM_004119.3

p.H821H

c.2463C>T

1 paper

NM_004119.3

p.T820S

c.2459C>G

9 papers

NM_004119.3

p.T820N

c.2459C>A

1 paper

NM_004119.3

p.G822W

c.2464G>T

3 papers

NM_004119.3

p.G822R

c.2464G>C

3 papers

NM_004119.3

p.G822R

c.2464G>A

1 paper

NM_004119.3

p.T820S

c.2458A>T

1 paper

NM_004119.3

p.T820A

c.2458A>G

1 paper

NM_004119.3

p.G822E

c.2465G>A

3 papers

NM_004119.3

p.V819A

c.2456T>C

1 paper

NM_004119.3

p.L818insFs

c.2454dupT

3 papers

NM_004119.3

p.V819I

c.2455G>A