Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.N816K

c.2448C>A

Surrounding Variants

1 paper

NM_004119.3

p.N816N

c.2448C>T

1 paper

NM_004119.3

p.N816K

c.2448C>G

2 papers

NM_004119.3

p.V817M

c.2449G>A

1 paper

NM_004119.3

p.N816I

c.2447A>T

1 paper

NM_004119.3

p.R815S

c.2445G>T

1 paper

NM_004119.3

p.R815S

c.2445G>C

1 paper

NM_004119.3

p.R815K

c.2444G>A

1 paper

NM_004119.3

p.L818insFs

c.2454dupT

3 papers

NM_004119.3

p.V819I

c.2455G>A

3 papers

NM_004119.3

p.A814V

c.2441C>T

1 paper

NM_004119.3

p.A814G

c.2441C>G

1 paper

NM_004119.3

p.A814D

c.2441C>A