Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.R810*

c.2428A>T

Surrounding Variants

1 paper

NM_004119.3

p.R810G

c.2428A>G

1 paper

NM_004119.3

p.R810S

c.2430A>T

1 paper

NM_004119.3

p.R810S

c.2430A>C

1 paper

NM_004119.3

p.D811H

c.2431G>C

1 paper

NM_004119.3

p.D811V

c.2432A>T

1 paper

NM_004119.3

p.D811A

c.2432A>C

1 paper

NM_004119.3

p.V808I

c.2422G>A

3 papers

NM_004119.3

p.C807C

c.2421T>C

1 paper

NM_004119.3

p.L812P

c.2435T>C

1 paper

NM_004119.3

p.C807*

c.2421T>A

3 papers

NM_004119.3

p.C807S

c.2420G>C

1 paper

NM_004119.3

p.C807Y

c.2420G>A