Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.C681S

c.2041T>A

Surrounding Variants

1 paper

NM_004119.3

p.C681S

c.2042G>C

2 papers

NM_004119.3

p.C681Y

c.2042G>A

79 papers

NM_004119.3

p.A680V

c.2039C>T

1 paper

NM_004119.3

p.A680E

c.2039C>A

1 paper

NM_004119.3

p.A680delFs

c.2038delC

2 papers

NM_004119.3

p.A680T

c.2038G>A

1 paper

NM_004119.3

p.A680fs

c.2038_2039fs

1 paper

NM_004119.3

p.G679E

c.2036G>A

1 paper

NM_004119.3

p.G679W

c.2035G>T

3 papers

NM_004119.3

p.G679R

c.2035G>C

3 papers

NM_004119.3

p.G679R

c.2035G>A

1 paper

NM_004119.3

p.L683P

c.2048T>C