Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.E672_N673insA

c.2014_2018ins3

Surrounding Variants

1 paper

NM_004119.3

p.E672*

c.2014G>T

1 paper

NM_004119.3

p.E672K

c.2014G>A

1 paper

NM_004119.3

p.E672fs

c.2014_2015fs

1 paper

NM_004119.3

p.H671H

c.2013C>T

1 paper

NM_004119.3

p.E672G

c.2015A>G

1 paper

NM_004119.3

p.H671Y

c.2011C>T

1 paper

NM_004119.3

p.I674N

c.2021T>A

2 papers

NM_004119.3

p.G669E

c.2006G>A

2 papers

NM_004119.3

p.G669R

c.2005G>C

2 papers

NM_004119.3

p.G669R

c.2005G>A

1 paper

NM_004119.3

p.V675A

c.2024T>C

1 paper

NM_004119.3

p.L668P

c.2003T>C