Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.Q667fs

c.1999_2000fs

Surrounding Variants

1 paper

NM_004119.3

p.Q667E

c.1999C>G

3 papers

NM_004119.3

p.Q667delFs

c.1999delG

1 paper

NM_004119.3

p.Q667H

c.2001G>T

2 papers

NM_004119.3

p.Q667fs

c.1999_2000fs

1 paper

NM_004119.3

p.Q667H

c.2001G>C

1 paper

NM_004119.3

p.Q667Q

c.2001G>A

1 paper

NM_004119.3

p.T666P

c.1996A>C

1 paper

NM_004119.3

p.L668P

c.2003T>C

1 paper

NM_004119.3

p.M665I

c.1995G>T

1 paper

NM_004119.3

p.M665I

c.1995G>C

1 paper

NM_004119.3

p.M665I

c.1995G>A

1 paper

NM_004119.3

p.M665T

c.1994T>C