Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

21 papers

NM_004119.3

p.V592G

c.1775T>G

Surrounding Variants

1 paper

NM_004119.3

p.V592ins9

c.1775_1776ins27

1 paper

NM_004119.3

p.Y591ins3

c.1771_1772ins9

1 paper

NM_004119.3

p.V592ins7

c.1775_1776ins21

83 papers

NM_004119.3

p.V592A

c.1775T>C

21 papers

NM_004119.3

p.V592D

c.1775T>A

2 papers

NM_004119.3

p.V579_V592ins4

c.1736_1774dup39

1 paper

NM_004119.3

p.V592ins7

c.1775_1776ins21

2 papers

NM_004119.3

p.V592fs

c.1774_1775fs

2 papers

NM_004119.3

p.V592V

c.1776T>C

2 papers

NM_004119.3

p.V592fs

c.1774_1775fs

1 paper

NM_004119.3

p.E588_V592del0

c.1764_1775del12

3 papers

NM_004119.3

p.V592F

c.1774G>T