Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.F590insFs

c.1769_1770ins16

Surrounding Variants

1 paper

NM_004119.3

p.F590ins12

c.1769_1770ins36

1 paper

NM_004119.3

p.F590ins11

c.1769_1770ins33

1 paper

NM_004119.3

p.F590ins5

c.1769_1770ins15

1 paper

NM_004119.3

p.F590ins13

c.1769_1770ins39

2 papers

NM_004119.3

p.F590ins1

c.1769_1770insAGC

2 papers

NM_004119.3

p.F590insFs

c.1768_1769insA

2 papers

NM_004119.3

p.F590V

c.1768T>G

7 papers

NM_004119.3

p.F590L

c.1768T>C

1 paper

NM_004119.3

p.M578_Y589del12

c.1732_1766del36

7 papers

NM_004119.3

p.F590L

c.1770C>G

1 paper

NM_004119.3

p.F590ins12

c.1769_1770ins36

2 papers

NM_004119.3

p.M578_F590ins4

c.1734_1769dup36