Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.G583_S584delFs

c.1747_1750del4

Surrounding Variants

1 paper

NM_004119.3

p.S585ins8

c.1753_1754ins24

1 paper

NM_004119.3

p.S585P

c.1753T>C

3 papers

NM_004119.3

p.S584delFs

c.1751delG

1 paper

NM_004119.3

p.G583fs

c.1747_1748fs

1 paper

NM_004119.3

p.S585fs

c.1753_1754fs

1 paper

NM_004119.3

p.G583V

c.1748G>T

1 paper

NM_004119.3

p.G583A

c.1748G>C

2 papers

NM_004119.3

p.G583D

c.1748G>A

1 paper

NM_004119.3

p.S585L

c.1754C>T

1 paper

NM_004119.3

p.S585delFs

c.1753delA

2 papers

NM_004119.3

p.G583R

c.1747G>C

13 papers

NM_004119.3

p.G583S

c.1747G>A