Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.Q569H

c.1707A>C

Surrounding Variants

1 paper

NM_004119.3

p.Q569H

c.1707A>T

1 paper

NM_004119.3

p.Q569fs

c.1705_1706fs

1 paper

NM_004119.3

p.F570L

c.1708T>C

1 paper

NM_004119.3

p.Q569L

c.1706A>T

1 paper

NM_004119.3

p.Q569E

c.1705C>G

6 papers

NM_004119.3

p.Q569fs

c.1705_1706fs

1 paper

NM_004119.3

p.F570L

c.1710T>G

1 paper

NM_004119.3

p.F570F

c.1710T>C

1 paper

NM_004119.3

p.F570L

c.1710T>A

1 paper

NM_004119.3

p.K568_Q569Splc

c.1705-1G>T

1 paper

NM_004119.3

p.R571W

c.1711A>T

2 papers

NM_004119.3

p.Q569_R571delFs

c.1705_1712del8