Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.V213_V214insT

c.637_641ins3

Surrounding Variants

1 paper

NM_004119.3

p.V213G

c.638T>G

1 paper

NM_004119.3

p.V214L

c.640G>C

2 papers

NM_004119.3

p.V214I

c.640G>A

1 paper

NM_004119.3

p.V214A

c.641T>C

1 paper

NM_004119.3

p.P211T

c.631C>A

1 paper

NM_004119.3

p.V214_K215delFs

c.640_644del5

20 papers

NM_004119.3

p.E209D

c.627A>T

1 paper

NM_004119.3

p.K216insFs

c.647dupA

2 papers

NM_004119.3

p.E209A

c.626A>C

1 paper

NM_004119.3

p.E209K

c.625G>A

1 paper

NM_004119.3

p.E217fs

c.649_650fs

1 paper

NM_004119.3

p.E217V

c.650A>T