Varaico: Literature-Extracted Genetic Variants

FLT3

2,401 papers

RefSeq Summary

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, whic...

Pfam Domains

igaa 258–343UCSCImmunoglobulin domain

PK_Tyr_Ser-Thraa 610–943UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 3

HGNC Alias Symbols

FLK2; CD135

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004119.3

p.G9S

c.25G>A

Surrounding Variants

1 paper

NM_004119.3

p.G9D

c.26G>A

1 paper

NM_004119.3

p.G8insFs

c.23dupG

1 paper

NM_004119.3

p.G8A

c.23G>C

1 paper

NM_004119.3

p.G9G

c.27C>A

1 paper

NM_004119.3

p.G8R

c.22G>C

1 paper

NM_004119.3

p.Q10delFs

c.28delG

18 papers

NM_004119.3

p.D7G

c.20A>G

2 papers

NM_004119.3

p.D7A

c.20A>C

1 paper

NM_004119.3

p.D7N

c.19G>A

1 paper

NM_004119.3

p.R6R

c.18C>T

1 paper

NM_004119.3

p.R6insFs

c.17dupG

1 paper

NM_004119.3

p.R6delFs

c.16delG