Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 1119 variants

29 papers

NM_182925.5

p.P1137L

c.3410C>T

21 papers

NM_182925.5

p.H890Q

c.2670C>G

21 papers

NM_182925.5

p.P954S

c.2860C>T

21 papers

NM_182925.5

p.P1114L

c.3341C>T

20 papers

NM_182925.5

p.T494A

c.1480A>G

20 papers

NM_182925.5

p.H890Q

c.2670C>A

20 papers

NM_182925.5

p.R1041W

c.3121C>T

19 papers

NM_182925.5

p.H1035R

c.3104A>G

19 papers

NM_182925.5

p.R1041Q

c.3122G>A

17 papers

NM_182925.5

p.G857R

c.2569G>C

17 papers

NM_182925.5

p.G857R

c.2569G>A

16 papers

NM_182925.5

p.R1324L

c.3971G>T