Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182925.5

p.A1326fs

c.3976_3977fs

Surrounding Variants

1 paper

NM_182925.5

p.A1326delFs

c.3976delC

1 paper

NM_182925.5

p.R1327Q

c.3980G>A

1 paper

NM_182925.5

p.G1328V

c.3983G>T

16 papers

NM_182925.5

p.R1324L

c.3971G>T

3 papers

NM_182925.5

p.R1324P

c.3971G>C

3 papers

NM_182925.5

p.G1329S

c.3985G>A

1 paper

NM_182925.5

p.Q1330E

c.3988C>G

1 paper

NM_182925.5

p.E1323Q

c.3967G>C

7 papers

NM_182925.5

p.R1321Q

c.3962G>A

1 paper

NM_182925.5

p.R1321W

c.3961C>T

3 papers

NM_182925.5

p.R1320Q

c.3959G>A

2 papers

NM_182925.5

p.R1320W

c.3958C>T