Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182925.5

p.R1310G

c.3928A>G

Surrounding Variants

1 paper

NM_182925.5

p.A1307S

c.3919G>T

1 paper

NM_182925.5

p.A1307T

c.3919G>A

1 paper

NM_182925.5

p.P1313P

c.3939T>A

1 paper

NM_182925.5

p.D1314A

c.3941A>C

1 paper

NM_182925.5

p.D1314D

c.3942C>T

2 papers

NM_182925.5

p.S1315F

c.3944C>T

1 paper

NM_182925.5

p.Q1316K

c.3946C>A

8 papers

NM_182925.5

p.G1303A

c.3908G>C

1 paper

NM_182925.5

p.Q1316H

c.3948A>T

1 paper

NM_182925.5

p.Q1316H

c.3948A>C

1 paper

NM_182925.5

p.G1317E

c.3950G>A

1 paper

NM_182925.5

p.P1302S

c.3904C>T