Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182925.5

p.Y1068*

c.3204C>A

Surrounding Variants

1 paper

NM_182925.5

p.Y1068*

c.3204C>G

1 paper

NM_182925.5

p.V1069I

c.3205G>A

1 paper

NM_182925.5

p.Y1068delFs

c.3204delG

1 paper

NM_182925.5

p.Y1068F

c.3203A>T

1 paper

NM_182925.5

p.Y1068N

c.3202T>A

1 paper

NM_182925.5

p.D1067_Y1068insFs

c.3201_3202insG

1 paper

NM_182925.5

p.V1069_R1070insFs

c.3207_3208insA

1 paper

NM_182925.5

p.R1070C

c.3208C>T

1 paper

NM_182925.5

p.R1070S

c.3208C>A

3 papers

NM_182925.5

p.R1070L

c.3209G>T

2 papers

NM_182925.5

p.D1067N

c.3199G>A

1 paper

NM_182925.5

p.R1070H

c.3209G>A