Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_182925.5

p.N1042S

c.3125A>G

Surrounding Variants

1 paper

NM_182925.5

p.R1041L

c.3122G>T

14 papers

NM_182925.5

p.R1041P

c.3122G>C

19 papers

NM_182925.5

p.R1041Q

c.3122G>A

20 papers

NM_182925.5

p.R1041W

c.3121C>T

1 paper

NM_182925.5

p.R1041G

c.3121C>G

15 papers

NM_182925.5

p.L1044P

c.3131T>C

2 papers

NM_182925.5

p.A1040D

c.3119C>A

1 paper

NM_182925.5

p.L1045P

c.3134T>C

1 paper

NM_182925.5

p.A1039V

c.3116C>T

1 paper

NM_182925.5

p.A1039D

c.3116C>A

1 paper

NM_182925.5

p.L1038Q

c.3113T>A

2 papers

NM_182925.5

p.S1046L

c.3137C>T