Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_182925.5

p.H1035Q

c.3105C>G

Surrounding Variants

9 papers

NM_182925.5

p.H1035Q

c.3105C>A

1 paper

NM_182925.5

p.H1035L

c.3104A>T

19 papers

NM_182925.5

p.H1035R

c.3104A>G

1 paper

NM_182925.5

p.R1036G

c.3106A>G

1 paper

NM_182925.5

p.I1034S

c.3101T>G

3 papers

NM_182925.5

p.D1037Y

c.3109G>T

5 papers

NM_182925.5

p.D1037H

c.3109G>C

3 papers

NM_182925.5

p.D1037E

c.3111C>G

4 papers

NM_182925.5

p.D1037E

c.3111C>A

2 papers

NM_182925.5

p.C1033G

c.3097T>G

1 paper

NM_182925.5

p.L1038Q

c.3113T>A

1 paper

NM_182925.5

p.A1039V

c.3116C>T