Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182925.5

p.R994W

c.2980C>T

Surrounding Variants

1 paper

NM_182925.5

p.R993S

c.2979G>T

1 paper

NM_182925.5

p.R993S

c.2979G>C

1 paper

NM_182925.5

p.R994Q

c.2981G>A

1 paper

NM_182925.5

p.R993M

c.2978G>T

1 paper

NM_182925.5

p.A995P

c.2983G>C

1 paper

NM_182925.5

p.A992fs

c.2974_2975fs

1 paper

NM_182925.5

p.A992T

c.2974G>A

1 paper

NM_182925.5

p.S996F

c.2987C>T

1 paper

NM_182925.5

p.G991E

c.2972G>A

1 paper

NM_182925.5

p.G990V

c.2969G>T

1 paper

NM_182925.5

p.P997delFs

c.2990delG

1 paper

NM_182925.5

p.D998N

c.2992G>A