Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182925.5

p.N911T

c.2732A>C

Surrounding Variants

1 paper

NM_182925.5

p.V909V

c.2727G>A

1 paper

NM_182925.5

p.L913F

c.2737C>T

1 paper

NM_182925.5

p.G914W

c.2740G>T

6 papers

NM_182925.5

p.G914R

c.2740G>C

5 papers

NM_182925.5

p.G914R

c.2740G>A

3 papers

NM_182925.5

p.L913del1

c.2737_2738delGAG

1 paper

NM_182925.5

p.N908H

c.2722A>C

1 paper

NM_182925.5

p.L907insFs

c.2721dupC

10 papers

NM_182925.5

p.A915P

c.2743G>C

3 papers

NM_182925.5

p.A915E

c.2744C>A

12 papers

NM_182925.5

p.C916W

c.2748C>G

1 paper

NM_182925.5

p.N905delFs

c.2714delT