Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

15 papers

NM_182925.5

p.L893V

c.2677C>G

Surrounding Variants

2 papers

NM_182925.5

p.A892T

c.2674G>A

1 paper

NM_182925.5

p.M894del1

c.2680_2682delCAT

1 paper

NM_182925.5

p.R891C

c.2671C>T

21 papers

NM_182925.5

p.H890Q

c.2670C>G

20 papers

NM_182925.5

p.H890Q

c.2670C>A

3 papers

NM_182925.5

p.E896*

c.2686G>T

1 paper

NM_182925.5

p.E896fs

c.2686_2687fs

1 paper

NM_182925.5

p.H890Y

c.2668C>T

1 paper

NM_182925.5

p.K898R

c.2693A>G

1 paper

NM_182925.5

p.K898N

c.2694G>T

1 paper

NM_182925.5

p.K898N

c.2694G>C

1 paper

NM_182925.5

p.E896_I899delFs

c.2686_2695del10