Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_182925.5

p.A877T

c.2629G>A

Surrounding Variants

1 paper

NM_182925.5

p.V876L

c.2626G>T

1 paper

NM_182925.5

p.V876L

c.2626G>C

14 papers

NM_182925.5

p.V878M

c.2632G>A

2 papers

NM_182925.5

p.V876M

c.2626G>A

1 paper

NM_182925.5

p.D874V

c.2621A>T

1 paper

NM_182925.5

p.C873_D874ins11

c.2617_2621ins33

3 papers

NM_182925.5

p.S872N

c.2615G>A

2 papers

NM_182925.5

p.E883Splc

c.2647+1G>T

1 paper

NM_182925.5

p.E883Splc

c.2647+1G>A

1 paper

NM_182925.5

p.E883Splc

c.2647+2T>C

1 paper

NM_182925.5

p.I867V

c.2599A>G

2 papers

NM_182925.5

p.G866S

c.2596G>A