Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182925.5

p.G854A

c.2561G>C

Surrounding Variants

5 papers

NM_182925.5

p.G854R

c.2560G>C

13 papers

NM_182925.5

p.G854S

c.2560G>A

11 papers

NM_182925.5

p.A855T

c.2563G>A

1 paper

NM_182925.5

p.Y853fs

c.2557_2558fs

2 papers

NM_182925.5

p.G852V

c.2555G>T

3 papers

NM_182925.5

p.G852C

c.2554G>T

5 papers

NM_182925.5

p.G852R

c.2554G>C

5 papers

NM_182925.5

p.G852S

c.2554G>A

1 paper

NM_182925.5

p.G857W

c.2569G>T

17 papers

NM_182925.5

p.G857R

c.2569G>C

17 papers

NM_182925.5

p.G857R

c.2569G>A

1 paper

NM_182925.5

p.V859M

c.2575G>A