Varaico: Literature-Extracted Genetic Variants

FLT4

789 papers

RefSeq Summary

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. M...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 28–142UCSCVEGFR1-3, N-terminal Ig-like domain

Ig_2aa 137–224UCSCImmunoglobulin domain

VEGFR-1-like_Ig-likeaa 143–224UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

Ig_3aa 231–314UCSCImmunoglobulin domain

Ig_VEGFR-1-like_5thaa 419–553UCSCVEGFR-1-like, immunoglobulin-like domain

I-setaa 678–765UCSCImmunoglobulin I-set domain

Gene Aliases

HGNC Name

fms related receptor tyrosine kinase 4

HGNC Alias Symbols

VEGFR3; PCL; VEGFR-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_182925.5

p.P500S

c.1498C>T

Surrounding Variants

1 paper

NM_182925.5

p.P500A

c.1498C>G

1 paper

NM_182925.5

p.E502*

c.1504G>T

5 papers

NM_182925.5

p.E502K

c.1504G>A

1 paper

NM_182925.5

p.V498M

c.1492G>A

1 paper

NM_182925.5

p.T493_I501del9

c.1477_1502del27

2 papers

NM_182925.5

p.A497V

c.1490C>T

1 paper

NM_182925.5

p.S503delFs

c.1507_1508delCT

1 paper

NM_182925.5

p.T494M

c.1481C>T

20 papers

NM_182925.5

p.T494A

c.1480A>G

2 papers

NM_182925.5

p.W507*

c.1520G>A

2 papers

NM_182925.5

p.W507*

c.1521G>A

1 paper

NM_182925.5

p.V492M

c.1474G>A