Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001455.4

p.A53T

c.157G>A

Surrounding Variants

3 papers

NM_001455.4

p.A53A

c.159C>T

1 paper

NM_001455.4

p.S55A

c.163T>G

1 paper

NM_001455.4

p.E50D

c.150G>C

1 paper

NM_001455.4

p.E50D

c.150G>T

1 paper

NM_001455.4

p.E50K

c.148G>A

1 paper

NM_001455.4

p.G49E

c.146G>A

2 papers

NM_001455.4

p.P47L

c.140C>T

6 papers

NM_001455.4

p.D62N

c.184G>A

1 paper

NM_001455.4

p.D62E

c.186C>A

1 paper

NM_001455.4

p.D62E

c.186C>G

2 papers

NM_001455.4

p.D63N

c.187G>A

1 paper

NM_001455.4

p.D68N

c.202G>A