Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001455.4

p.P135Q

c.404C>A

Surrounding Variants

1 paper

NM_001455.4

p.P138L

c.413C>T

2 papers

NM_001455.4

p.A140S

c.418G>T

8 papers

NM_001455.4

p.A140V

c.419C>T

1 paper

NM_001455.4

p.A141T

c.421G>A

1 paper

NM_001455.4

p.G142A

c.425G>C

2 papers

NM_001455.4

p.G143S

c.427G>A

2 papers

NM_001455.4

p.G143D

c.428G>A

2 papers

NM_001455.4

p.G143A

c.428G>C

3 papers

NM_001455.4

p.G143V

c.428G>T

1 paper

NM_001455.4

p.Q128_P129ins0

c.383_385dupAGC

1 paper

NM_001455.4

p.L127fs

c.379_380fs

1 paper

NM_001455.4

p.L127delFs

c.379delC