Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001455.4

p.T179A

c.535A>G

Surrounding Variants

2 papers

NM_001455.4

p.R177W

c.529C>T

1 paper

NM_001455.4

p.K176R

c.527A>G

1 paper

NM_001455.4

p.D175E

c.525C>G

1 paper

NM_001455.4

p.D175H

c.523G>C

1 paper

NM_001455.4

p.K176_R177insFs

c.526_529dup4

2 papers

NM_001455.4

p.P174S

c.520C>T

3 papers

NM_001455.4

p.S173F

c.518C>T

1 paper

NM_001455.4

p.S173A

c.517T>G

2 papers

NM_001455.4

p.V188L

c.562G>C

2 papers

NM_001455.4

p.V188L

c.562G>T

1 paper

NM_001455.4

p.A169A

c.507C>T

3 papers

NM_001455.4

p.R168R

c.504C>T