Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001455.4

p.R249R

c.747G>A

Surrounding Variants

1 paper

NM_001455.4

p.R250Q

c.749G>A

1 paper

NM_001455.4

p.R248W

c.742C>T

1 paper

NM_001455.4

p.A251A

c.753T>C

9 papers

NM_001455.4

p.S253A

c.757T>G

1 paper

NM_001455.4

p.A246insFs

c.737dupC

2 papers

NM_001455.4

p.A246fs

c.736_737fs

2 papers

NM_001455.4

p.K259*

c.775A>T

1 paper

NM_001455.4

p.G240E

c.719G>A

1 paper

NM_001455.4

p.Y260H

c.778T>C

1 paper

NM_001455.4

p.T261I

c.782C>T

1 paper

NM_001455.4

p.K262M

c.785A>T

1 paper

NM_001455.4

p.N237_K242del6

c.709_725del18