Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001455.4

p.C362W

c.1086C>G

Surrounding Variants

1 paper

NM_001455.4

p.C362F

c.1085G>T

1 paper

NM_001455.4

p.T363M

c.1088C>T

1 paper

NM_001455.4

p.D371N

c.1111G>A

4 papers

NM_001455.4

p.A352A

c.1056C>G

1 paper

NM_001455.4

p.N379N

c.1137T>C

1 paper

NM_001455.4

p.P345L

c.1034C>T

7 papers

NM_001455.4

p.D380fs

c.1138_1139fs

14 papers

NM_001455.4

p.G381insFs

c.1141dupG

1 paper

NM_001455.4

p.S344A

c.1030T>G

8 papers

NM_001455.4

p.L382fs

c.1144_1145fs

6 papers

NM_001455.4

p.L382fs

c.1144_1145fs

1 paper

NM_001455.4

p.T383A

c.1147A>G