Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001455.4

p.S399A

c.1195T>G

Surrounding Variants

2 papers

NM_001455.4

p.P397R

c.1190C>G

1 paper

NM_001455.4

p.P397S

c.1189C>T

2 papers

NM_001455.4

p.T395T

c.1185G>A

1 paper

NM_001455.4

p.D392G

c.1175A>G

1 paper

NM_001455.4

p.D388G

c.1163A>G

2 papers

NM_001455.4

p.L386F

c.1156C>T

2 papers

NM_001455.4

p.F414Y

c.1241T>A

1 paper

NM_001455.4

p.T383A

c.1147A>G

1 paper

NM_001455.4

p.P415L

c.1244C>T

8 papers

NM_001455.4

p.L382fs

c.1144_1145fs

6 papers

NM_001455.4

p.L382fs

c.1144_1145fs

14 papers

NM_001455.4

p.G381insFs

c.1141dupG