Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001455.4

p.T458S

c.1373C>G

Surrounding Variants

1 paper

NM_001455.4

p.T458S

c.1372A>T

2 papers

NM_001455.4

p.P456Q

c.1367C>A

1 paper

NM_001455.4

p.Q452*

c.1354C>T

1 paper

NM_001455.4

p.Y465C

c.1394A>G

1 paper

NM_001455.4

p.Q449P

c.1346A>C

1 paper

NM_001455.4

p.M448T

c.1343T>C

2 papers

NM_001455.4

p.P447A

c.1339C>G

1 paper

NM_001455.4

p.S476L

c.1427C>T

1 paper

NM_001455.4

p.F435V

c.1303T>G

1 paper

NM_001455.4

p.S482N

c.1445G>A

1 paper

NM_001455.4

p.D483insFs

c.1447_1448insG

1 paper

NM_001455.4

p.D483H

c.1447G>C