Varaico: Literature-Extracted Genetic Variants

FOXO3

295 papers

RefSeq Summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of gen...

Pfam Domains

Forkheadaa 157–245UCSCForkhead domain

FOXO_KIX_bdgaa 432–511UCSCKIX-binding domain of forkhead box O, CR2

FOXO-TADaa 604–645UCSCTransactivation domain of FOXO protein family

Gene Aliases

HGNC Name

forkhead box O3

HGNC Previous Symbols

FKHRL1; FOXO3A

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_001455.4

p.R506H

c.1517G>A

Surrounding Variants

1 paper

NM_001455.4

p.P515L

c.1544C>T

1 paper

NM_001455.4

p.Q495K

c.1483C>A

1 paper

NM_001455.4

p.A521S

c.1561G>T

1 paper

NM_001455.4

p.Q525R

c.1574A>G

1 paper

NM_001455.4

p.L528V

c.1582T>G

1 paper

NM_001455.4

p.D483H

c.1447G>C

1 paper

NM_001455.4

p.D483insFs

c.1447_1448insG

1 paper

NM_001455.4

p.S482N

c.1445G>A

1 paper

NM_001455.4

p.S476L

c.1427C>T

1 paper

NM_001455.4

p.G542delFs

c.1625delG

1 paper

NM_001455.4

p.G542S

c.1624G>A

1 paper

NM_001455.4

p.G542fs

c.1624_1625fs