Varaico: Literature-Extracted Genetic Variants

FRAT2

12 papers

RefSeq Summary

The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upr...

Pfam Domains

GSK-3_bindaa 1–142UCSCGlycogen synthase kinase-3 binding

GSK-3_bindaa 139–214UCSCGlycogen synthase kinase-3 binding

Gene Aliases

HGNC Name

FRAT regulator of Wnt signaling pathway 2

HGNC Previous Names

FRAT regulator of WNT signaling pathway 2; frequently rearranged in advanced T-cell lymphomas 2; FRAT2, WNT signaling pathway regulator

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012083.3

p.E19V

c.56A>T

Surrounding Variants

1 paper

NM_012083.3

p.E7K

c.19G>A

1 paper

NM_012083.3

p.A56T

c.166G>A

1 paper

NM_012083.3

p.A83T

c.247G>A

1 paper

NM_012083.3

p.A100A

c.300T>A

1 paper

NM_012083.3

p.G116_Y128delFs

c.346_383del38

1 paper

NM_012083.3

p.A139delFs

c.415delC

1 paper

NM_012083.3

p.A139fs

c.415_416fs

1 paper

NM_012083.3

p.G216*

c.646G>T