Varaico: Literature-Extracted Genetic Variants

FRK

140 papers

RefSeq Summary

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [...

Pfam Domains

SH3_1aa 48–102UCSCSH3 domain

SH2aa 116–193UCSCSH2 domain

PK_Tyr_Ser-Thraa 234–487UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fyn related Src family tyrosine kinase

HGNC Previous Symbol

PTK5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002031.3

p.A371V

c.1112C>T

Surrounding Variants

1 paper

NM_002031.3

p.G374*

c.1120G>T

1 paper

NM_002031.3

p.V378G

c.1133T>G

1 paper

NM_002031.3

p.G363C

c.1087G>T

1 paper

NM_002031.3

p.F379del1

c.1135_1136delAAA

1 paper

NM_002031.3

p.V362A

c.1085T>C

1 paper

NM_002031.3

p.K380N

c.1140G>T

1 paper

NM_002031.3

p.K380N

c.1140G>C

1 paper

NM_002031.3

p.V362I

c.1084G>A

1 paper

NM_002031.3

p.L361P

c.1082T>C

1 paper

NM_002031.3

p.L361F

c.1081C>T

1 paper

NM_002031.3

p.D354E

c.1062T>G

1 paper

NM_002031.3

p.D354E

c.1062T>A