Varaico: Literature-Extracted Genetic Variants

FRK

140 papers

RefSeq Summary

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [...

Pfam Domains

SH3_1aa 48–102UCSCSH3 domain

SH2aa 116–193UCSCSH2 domain

PK_Tyr_Ser-Thraa 234–487UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fyn related Src family tyrosine kinase

HGNC Previous Symbol

PTK5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002031.3

p.E346G

c.1037A>G

Surrounding Variants

1 paper

NM_002031.3

p.R348W

c.1042C>T

1 paper

NM_002031.3

p.R348Q

c.1043G>A

1 paper

NM_002031.3

p.Y350C

c.1049A>G

2 papers

NM_002031.3

p.H352N

c.1054C>A

1 paper

NM_002031.3

p.A339A

c.1017C>T

1 paper

NM_002031.3

p.D354E

c.1062T>G

1 paper

NM_002031.3

p.D354E

c.1062T>A

1 paper

NM_002031.3

p.M334I

c.1002G>T

1 paper

NM_002031.3

p.M334I

c.1002G>C

1 paper

NM_002031.3

p.M334I

c.1002G>A

1 paper

NM_002031.3

p.L361F

c.1081C>T

1 paper

NM_002031.3

p.L361P

c.1082T>C