Varaico: Literature-Extracted Genetic Variants

FRK

140 papers

RefSeq Summary

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [...

Pfam Domains

SH3_1aa 48–102UCSCSH3 domain

SH2aa 116–193UCSCSH2 domain

PK_Tyr_Ser-Thraa 234–487UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fyn related Src family tyrosine kinase

HGNC Previous Symbol

PTK5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002031.3

p.Y193C

c.578A>G

Surrounding Variants

2 papers

NM_002031.3

p.Y193*

c.579C>G

2 papers

NM_002031.3

p.Y193*

c.579C>A

1 paper

NM_002031.3

p.V190V

c.570G>A

2 papers

NM_002031.3

p.E188K

c.562G>A

1 paper

NM_002031.3

p.S184*

c.551C>G

1 paper

NM_002031.3

p.S184*

c.551C>A

1 paper

NM_002031.3

p.F183_S184delFs

c.549_550delAA

1 paper

NM_002031.3

p.R181I

c.542G>T

1 paper

NM_002031.3

p.R179Q

c.536G>A

2 papers

NM_002031.3

p.R179*

c.535C>T

1 paper

NM_002031.3

p.D171Y

c.511G>T

1 paper

NM_002031.3

p.R166K

c.497G>A