Varaico: Literature-Extracted Genetic Variants

FRK

140 papers

RefSeq Summary

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [...

Pfam Domains

SH3_1aa 48–102UCSCSH3 domain

SH2aa 116–193UCSCSH2 domain

PK_Tyr_Ser-Thraa 234–487UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

fyn related Src family tyrosine kinase

HGNC Previous Symbol

PTK5

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_002031.3

p.S133L

c.398C>T

Surrounding Variants

1 paper

NM_002031.3

p.N135I

c.404A>T

1 paper

NM_002031.3

p.L131I

c.391T>A

1 paper

NM_002031.3

p.G138R

c.412G>C

1 paper

NM_002031.3

p.E127D

c.381G>T

1 paper

NM_002031.3

p.E127D

c.381G>C

1 paper

NM_002031.3

p.E127Q

c.379G>C

1 paper

NM_002031.3

p.D125E

c.375T>G

1 paper

NM_002031.3

p.D125E

c.375T>A

1 paper

NM_002031.3

p.R123I

c.368G>T

1 paper

NM_002031.3

p.R123K

c.368G>A

1 paper

NM_002031.3

p.R123G

c.367A>G

11 papers

NM_002031.3

p.G122R

c.364G>C