Varaico: Literature-Extracted Genetic Variants

FTO

395 papers

RefSeq Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron ...

Pfam Domains

FTO_NTDaa 36–325UCSCFTO catalytic domain

FTO_CTDaa 329–498UCSCFTO C-terminal domain

Gene Aliases

HGNC Name

FTO alpha-ketoglutarate dependent dioxygenase

HGNC Alias Symbols

KIAA1752; MGC5149; ALKBH9; IFEX9

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001080432.3

p.Y106H

c.316T>C

Surrounding Variants

1 paper

NM_001080432.3

p.Y106F

c.317A>T

7 papers

NM_001080432.3

p.G103D

c.308G>A

1 paper

NM_001080432.3

p.L109V

c.325C>G

2 papers

NM_001080432.3

p.G103S

c.307G>A

1 paper

NM_001080432.3

p.L109L

c.327G>A

1 paper

NM_001080432.3

p.T111N

c.332C>A

1 paper

NM_001080432.3

p.G100G

c.300T>A

2 papers

NM_001080432.3

p.R112T

c.335G>C

1 paper

NM_001080432.3

p.I99T

c.296T>C

1 paper

NM_001080432.3

p.I99V

c.295A>G

1 paper

NM_001080432.3

p.I97V

c.289A>G

2 papers

NM_001080432.3

p.T115M

c.344C>T