Varaico: Literature-Extracted Genetic Variants

FTO

395 papers

RefSeq Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron ...

Pfam Domains

FTO_NTDaa 36–325UCSCFTO catalytic domain

FTO_CTDaa 329–498UCSCFTO C-terminal domain

Gene Aliases

HGNC Name

FTO alpha-ketoglutarate dependent dioxygenase

HGNC Alias Symbols

KIAA1752; MGC5149; ALKBH9; IFEX9

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001363897.1

p.G154E

c.461G>A

Surrounding Variants

1 paper

NM_001080432.3

p.V179L

c.535G>C

4 papers

NM_001080432.3

p.G182A

c.545G>C

1 paper

NM_001080432.3

p.R178T

c.533G>C

1 paper

NM_001080432.3

p.F176F

c.528C>T

1 paper

NM_001080432.3

p.S184F

c.551C>T

1 paper

NM_001080432.3

p.F176I

c.526T>A

2 papers

NM_001080432.3

p.Y185C

c.554A>G

2 papers

NM_001080432.3

p.G187A

c.560G>C

1 paper

NM_001080432.3

p.G187V

c.560G>T

1 paper

NM_001080432.3

p.D189N

c.565G>A

1 paper

NM_001080432.3

p.L170W

c.509T>G

1 paper

NM_001080432.3

p.P169S

c.505C>T