Varaico: Literature-Extracted Genetic Variants

FURIN

795 papers

RefSeq Summary

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branc...

Pfam Domains

S8_pro-domainaa 33–107UCSCPeptidase S8 pro-domain

Peptidase_S8aa 144–427UCSCSubtilase family

P_proproteinaa 484–570UCSCProprotein convertase P-domain

Gene Aliases

HGNC Name

furin, paired basic amino acid cleaving enzyme

HGNC Previous Symbols

PCSK3; FUR; PACE

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002569.4

p.K28_V29insFs

c.84_85insC

Surrounding Variants

1 paper

NM_002569.4

p.K28T

c.83A>C

1 paper

NM_002569.4

p.V29Fs

c.86delinsCCFs

1 paper

NM_002569.4

p.F30I

c.88T>A

1 paper

NM_002569.4

p.Q27K

c.79C>A

1 paper

NM_002569.4

p.Q27*

c.79C>T

1 paper

NM_002569.4

p.F30Y

c.89T>A

1 paper

NM_002569.4

p.T31A

c.91A>G

1 paper

NM_002569.4

p.T31I

c.92C>T

1 paper

NM_002569.4

p.G26R

c.76G>C

1 paper

NM_002569.4

p.Q25H

c.75G>C

1 paper

NM_002569.4

p.T33A

c.97A>G

1 paper

NM_002569.4

p.T33T

c.99G>A