Varaico: Literature-Extracted Genetic Variants

FUT6

105 papers

RefSeq Summary

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 ...

Pfam Domains

Glyco_tran_10_Naa 59–169UCSCFucosyltransferase, N-terminal

Glyco_transf_10aa 185–357UCSCGlycosyltransferase family 10 (fucosyltransferase) C-term

Gene Aliases

HGNC Name

fucosyltransferase 6

HGNC Alias Symbols

FT1A; FCT3A; FucT-VI; FLJ40754

Papers

RefSeq ID

Protein change

DNA change

1–12 of 109 variants

19 papers

NM_000150.4

p.E247K

c.739G>A

11 papers

NM_000150.4

p.P124S

c.370C>T

9 papers

NM_000150.4

p.Y315*

c.945C>A

7 papers

NM_000150.4

p.L20R

c.59T>G

6 papers

NM_000150.4

p.W143*

c.428G>A

6 papers

NM_000150.4

p.R326Q

c.977G>A

5 papers

NM_000150.4

p.R303G

c.907C>G

5 papers

NM_000150.4

p.Y315*

c.945C>G

4 papers

NM_000150.4

p.P167insFs

c.499_500insC

4 papers

NM_000150.4

p.F246F

c.738C>T

4 papers

NM_000150.4

p.T324M

c.971C>T

3 papers

NM_000150.4

p.R110*

c.328C>T