Varaico: Literature-Extracted Genetic Variants

FUT6

105 papers

RefSeq Summary

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 ...

Pfam Domains

Glyco_tran_10_Naa 59–169UCSCFucosyltransferase, N-terminal

Glyco_transf_10aa 185–357UCSCGlycosyltransferase family 10 (fucosyltransferase) C-term

Gene Aliases

HGNC Name

fucosyltransferase 6

HGNC Alias Symbols

FT1A; FCT3A; FucT-VI; FLJ40754

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_000150.4

p.F246F

c.738C>T

Surrounding Variants

19 papers

NM_000150.4

p.E247K

c.739G>A

1 paper

NM_000150.4

p.E247A

c.740A>C

1 paper

NM_000150.4

p.A245V

c.734C>T

1 paper

NM_000150.4

p.S249A

c.745T>G

1 paper

NM_000150.4

p.L244V

c.730C>G

1 paper

NM_000150.4

p.Y243Y

c.729T>C

3 papers

NM_000150.4

p.F242C

c.725T>G

1 paper

NM_000150.4

p.D253Y

c.757G>T

1 paper

NM_000150.4

p.Y254H

c.760T>C

1 paper

NM_000150.4

p.T256A

c.766A>G

1 paper

NM_000150.4

p.E257K

c.769G>A

1 paper

NM_000150.4

p.T236M

c.707C>T